Step 1:
The first step to converting 4.5211225781259E-6 to a fraction is to re-write 4.5211225781259E-6 in the form p/q where p and q are both positive integers. To start with, 4.5211225781259E-6 can be written as simply 4.5211225781259E-6/1 to technically be written as a fraction.
Step 2:
Next, we will count the number of fractional digits after the decimal point in 4.5211225781259E-6, which in this case is 16. For however many digits after the decimal point there are, we will multiply the numerator and denominator of 4.5211225781259E-6/1 each by 10 to the power of that many digits. So, in this case, we will multiply the numerator and denominator of 4.5211225781259E-6/1 each by 10000000000000000:
Step 3:
Now the last step is to simplify the fraction (if possible) by finding similar factors and cancelling them out, which leads to the following answer for 4.5211225781259E-6 as a fraction:
1/221184 / 1